We study the host/pathogen interactions of protozoan parasites, including Toxoplasma gondii, the causative agent of toxoplasmosis, and T. gondii‘s diarrhea-causing cousins Cryptosporidium parvum and Entamoeba histolytica.

We use the latest technologies, including next generation sequencing and mass spectrometry, to uncover parasite and host genes that are necessary for invasive or chronic infection in animals. We then use biochemistry, molecular and cell biology to define the how and why these pathogen and host genes are important.