Selected publications:


Mendoza Cavazos C, Knoll LJ. Entamoeba histolytica: Five facts about modeling a complex human disease in rodents. PLoS Pathog. 2020 Nov 12;16(11):e1008950. doi: 10.1371/journal.ppat.1008950. PMID: 33180884; PMCID: PMC7660559.

Wilson SK, Heckendorn J, Martorelli Di Genova B, Koch LL, Rooney PJ, Morrissette N, Lebrun M, Knoll LJ. A Toxoplasma gondii patatin-like phospholipase contributes to host cell invasion. PLoS Pathog. 2020 Jul 6;16(7):e1008650. doi: 10.1371/journal.ppat.1008650. PMID: 32628723; PMCID: PMC7365478.

Olson WJ, Martorelli Di Genova B, Gallego-Lopez G, Dawson AR, Stevenson D, Amador-Noguez D, Knoll LJ. Dual metabolomic profiling uncovers Toxoplasma manipulation of the host metabolome and the discovery of a novel parasite metabolic capability. PLoS Pathog. 2020 Apr 7;16(4):e1008432. doi: 10.1371/journal.ppat.1008432. PMID: 32255806; PMCID: PMC7164669.


Garfoot AL, Wilson GM, Coon JJ, Knoll LJ. Proteomic and transcriptomic analyses of early and late-chronic Toxoplasma gondii infection shows novel and stage specific transcripts. BMC Genomics. 2019 Nov 14;20(1):859. doi: 10.1186/s12864-019-6213-0. PMID: 31726967; PMCID: PMC6857164.

Arendt M, Elissa J, Schmidt N, Michael E, Potter N, Cook M, Knoll LJ. Investigating the role of interleukin 10 on Eimeria intestinal pathogenesis in broiler chickens. Vet Immunol Immunopathol. 2019 Dec;218:109934. doi: 10.1016/j.vetimm.2019.109934. Epub 2019 Aug 31. PMID: 31520870; PMCID: PMC6861699.

Martorelli Di Genova B, Wilson SK, Dubey JP, Knoll LJ. Intestinal delta-6-desaturase activity determines host range for Toxoplasma sexual reproduction. PLoS Biol. 2019 Aug 20;17(8):e3000364. doi: 10.1371/journal.pbio.3000364. PMID: 31430281; PMCID: PMC6701743.

Garfoot AL, Cervantes PW, Knoll LJ. Transcriptional Analysis Shows a Robust Host Response to Toxoplasma gondii during Early and Late Chronic Infection in Both Male and Female Mice. Infect Immun. 2019 Apr 23;87(5):e00024-19. doi: 10.1128/IAI.00024-19. PMID: 30858341; PMCID: PMC6479041.


Wilson SK, Knoll LJ. Patatin-like phospholipases in microbial infections with emerging roles in fatty acid metabolism and immune regulation by Apicomplexa. Mol Microbiol. 2018 Jan;107(1):34-46. doi: 10.1111/mmi.13871. Epub 2017 Nov 23. PMID: 29090840; PMCID: PMC5739999.

Knoll LJ, Hogan DA, Leong JM, Heitman J, Condit RC. Pearls collections: What we can learn about infectious disease and cancer. PLoS Pathog. 2018 Mar 29;14(3):e1006915. doi: 10.1371/journal.ppat.1006915. PMID: 29596508; PMCID: PMC5875890.


Milligan-Myhre K, Wilson SK, Knoll LJ. Developmental change in translation initiation alters the localization of a common microbial protein necessary for Toxoplasma chronic infection. Mol Microbiol. 2016 Dec;102(6):1086-1098. doi: 10.1111/mmi.13538. Epub 2016 Oct 14. PMID: 27671212; PMCID: PMC5161674.

Rall G, Knoll LJ. Development of Complex Models to Study Co- and Polymicrobial Infections and Diseases. PLoS Pathog. 2016 Sep 8;12(9):e1005858. doi: 10.1371/journal.ppat.1005858. PMID: 27607188; PMCID: PMC5015861.

Pittman KJ, Cervantes PW, Knoll LJ. Z-DNA Binding Protein Mediates Host Control of Toxoplasma gondii Infection. Infect Immun. 2016 Sep 19;84(10):3063-70. doi: 10.1128/IAI.00511-16. PMID: 27481249; PMCID: PMC5038082.

Knoll LJ. Functional Analysis of the Rhoptry Kinome during Chronic Toxoplasma gondii Infection. mBio. 2016 Jun 14;7(3):e00842-16. doi: 10.1128/mBio.00842-16. PMID: 27302762; PMCID: PMC4916387.

Knoll LJ. Conveying Discovery to a Broad Audience. PLoS Pathog. 2016 May 19;12(5):e1005425. doi: 10.1371/journal.ppat.1005425. PMID: 27196056; PMCID: PMC4873215.


Pittman KJ, Knoll LJ. Long-Term Relationships: the Complicated Interplay between the Host and the Developmental Stages of Toxoplasma gondii during Acute and Chronic Infections. Microbiol Mol Biol Rev. 2015 Dec;79(4):387-401. doi: 10.1128/MMBR.00027-15. PMID: 26335719; PMCID: PMC4557073.

Pittman KJ, Aliota MT, Knoll LJ. Dual transcriptional profiling of mice and Toxoplasma gondii during acute and chronic infection. BMC Genomics. 2014 Sep 20;15(1):806. doi: 10.1186/1471-2164-15-806. PMID: 25240600; PMCID: PMC4177681.

Neal LM, Knoll LJ. Toxoplasma gondii profilin promotes recruitment of Ly6Chi CCR2+ inflammatory monocytes that can confer resistance to bacterial infection. PLoS Pathog. 2014 Jun 12;10(6):e1004203. doi: 10.1371/journal.ppat.1004203. PMID: 24945711; PMCID: PMC4055779.

Tobin Magle C, Pittman KJ, Moser LA, Boldon KM, Knoll LJ. A toxoplasma patatin-like protein changes localization and alters the cytokine response during toxoplasmic encephalitis. Infect Immun. 2014 Feb;82(2):618-25. doi: 10.1128/IAI.00444-13. Epub 2013 Nov 25. PMID: 24478077; PMCID: PMC3911373.

Settles EW, Moser LA, Harris TH, Knoll LJ. Toxoplasma gondii upregulates interleukin-12 to prevent Plasmodium berghei-induced experimental cerebral malaria. Infect Immun. 2014 Mar;82(3):1343-53. doi: 10.1128/IAI.01259-13. Epub 2014 Jan 6. PMID: 24396042; PMCID: PMC3957979.

Payne AJ, Neal LM, Knoll LJ. Fusidic acid is an effective treatment against Toxoplasma gondii and Listeria monocytogenes in vitro, but not in mice. Parasitol Res. 2013 Nov;112(11):3859-63. doi: 10.1007/s00436-013-3574-1. Epub 2013 Aug 16. PMID: 23949312; PMCID: PMC4096717.

Moser LA, Pollard AM, Knoll LJ. A genome-wide siRNA screen to identify host factors necessary for growth of the parasite Toxoplasma gondii. PLoS One. 2013 Jun 28;8(6):e68129. doi: 10.1371/journal.pone.0068129. PMID: 23840822; PMCID: PMC3695992.

Hsiao CH, Luisa Hiller N, Haldar K, Knoll LJ. A HT/PEXEL motif in Toxoplasma dense granule proteins is a signal for protein cleavage but not export into the host cell. Traffic. 2013 May;14(5):519-31. doi: 10.1111/tra.12049. Epub 2013 Feb 26. PMID: 23356236; PMCID: PMC3622808.

Payne TM, Payne AJ, Knoll LJ. A Toxoplasma gondii mutant highlights the importance of translational regulation in the apicoplast during animal infection. Mol Microbiol. 2011 Dec;82(5):1204-16. doi: 10.1111/j.1365-2958.2011.07879.x. Epub 2011 Nov 7. PMID: 22059956; PMCID: PMC4348008.

Tobin CM, Knoll LJ. A patatin-like protein protects Toxoplasma gondii from degradation in a nitric oxide-dependent manner. Infect Immun. 2012 Jan;80(1):55-61. doi: 10.1128/IAI.05543-11. Epub 2011 Oct 17. PMID: 22006568; PMCID: PMC3255658.


Click here for a full list of publications at NCBI’s PubMed